Pediatric cancer charities partner to fund international collaborative research

Public release date: 4-Mar-2013
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Contact: Jenny Song
jenny@solvingkidscancer.org
212-588-6625
Solving Kids' Cancer

Solving Kids' Cancer, along with U.K.-based charities Neuroblastoma Alliance UK, J-A-C-K, and other European organizations have aligned forces to improve access to promising clinical trials for children with high-risk neuroblastoma in North America, the U.K. and Europe. The aim of the International Neuroblastoma Research Collaborative (INBRC) is to bring the cancer research community together to produce immunotherapy options to treat, control and prevent the recurrence of neuroblastoma in children. The new initiative mandates a collaboration of international cancer centers, offering a grant award of up to $500,000 (USD).

The pediatric cancer charities have partnered for the first time to create new treatments for children with neuroblastoma who at best, have a 5 percent chance of survival after relapse.

Neuroblastoma is a cancer of the sympathetic nervous system that most commonly occurs in infants and children under 5 years old. The cancer is usually discovered after it has spread. Half of all children are diagnosed with high-risk neuroblastoma, which is one of the most aggressively treated of all cancers. Standard treatments include months of chemotherapy, surgery, radiation, and stem cell transplant, followed by additional months of maintenance therapy.

"Even after such intense treatment, about 60 percent of children relapse within three years," said Scott Kennedy, the Executive Director of Solving Kids' Cancer. "Immunotherapy can offer these children less toxic and more effective treatments, and offers more potential of curing relapsed neuroblastoma than chemotherapy and radiation."

Immunotherapy for cancer has rapidly advanced in recent years and shown success in some adult cancers, but few options are available for children, especially in Europe.

"This collaboration is significant, not only because of the amount of funding but also because we are creating more access to clinical trials for children," said Richard Brown, Chair at J-A-C-K. "Alliances can bring new ideas; focus new energies; and produce new action to defeat a cancer that preys upon the youngest. By bringing together both the advocacy community and the scientific community to work across continents, we can only maximize the hope that options such as immunotherapy may offer to children affected by neuroblastoma."

Neuroblastoma Alliance UK's Chief Executive, Alison Moy, agreed, "We are really excited to be involved in this collaboration, which is taking parent advocacy and the involvement of charities in furthering research to a new level. As neuroblastoma only affects children, it is not considered a common cancer and therefore research funding has been limited. We believe that children should be able to access the best possible treatment, wherever that may be and that's why we support families to access clinical treatment abroad. We hope that through the INBRC project, more children from the U.K. will be able get effective treatment, wherever that trial is taking place."

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Solving Kids' Cancer

Created by two fathers who lost children to pediatric cancer, Solving Kids' Cancer is committed to significantly improving survivorship of the deadliest childhood cancers. 100% of all donations are used to find, fund, and manage clinical trials and scientific programs to rapidly develop more effective and less toxic treatments. Solving Kids' Cancer is a 501(c)(3) public charity. To learn more about our work, please visit www.solvingkidscancer.org.

J-A-C-K

Joining Against Cancer in Kids (J-A-C-K) provides advice and support for children and families wishing to undertake innovative or experimental clinical trials, treatments for neuroblastoma. For more information, visit www.J-A-C-K.org.

Neuroblastoma Alliance UK

Established in 2006, the Neuroblastoma Alliance UK helps children and families affected by neuroblastoma by providing financial assistance for children's treatment and support to families affected by the disease, as well as funding research. The charity, which was until recently known as the 2Simple Trust, has helped fund treatment for 21 children abroad. This is more than any other neuroblastoma charity in the UK. See more at www.childrenscancer.org.uk

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 4-Mar-2013
[ | E-mail | Share ]

Contact: Jenny Song
jenny@solvingkidscancer.org
212-588-6625
Solving Kids' Cancer

Solving Kids' Cancer, along with U.K.-based charities Neuroblastoma Alliance UK, J-A-C-K, and other European organizations have aligned forces to improve access to promising clinical trials for children with high-risk neuroblastoma in North America, the U.K. and Europe. The aim of the International Neuroblastoma Research Collaborative (INBRC) is to bring the cancer research community together to produce immunotherapy options to treat, control and prevent the recurrence of neuroblastoma in children. The new initiative mandates a collaboration of international cancer centers, offering a grant award of up to $500,000 (USD).

The pediatric cancer charities have partnered for the first time to create new treatments for children with neuroblastoma who at best, have a 5 percent chance of survival after relapse.

Neuroblastoma is a cancer of the sympathetic nervous system that most commonly occurs in infants and children under 5 years old. The cancer is usually discovered after it has spread. Half of all children are diagnosed with high-risk neuroblastoma, which is one of the most aggressively treated of all cancers. Standard treatments include months of chemotherapy, surgery, radiation, and stem cell transplant, followed by additional months of maintenance therapy.

"Even after such intense treatment, about 60 percent of children relapse within three years," said Scott Kennedy, the Executive Director of Solving Kids' Cancer. "Immunotherapy can offer these children less toxic and more effective treatments, and offers more potential of curing relapsed neuroblastoma than chemotherapy and radiation."

Immunotherapy for cancer has rapidly advanced in recent years and shown success in some adult cancers, but few options are available for children, especially in Europe.

"This collaboration is significant, not only because of the amount of funding but also because we are creating more access to clinical trials for children," said Richard Brown, Chair at J-A-C-K. "Alliances can bring new ideas; focus new energies; and produce new action to defeat a cancer that preys upon the youngest. By bringing together both the advocacy community and the scientific community to work across continents, we can only maximize the hope that options such as immunotherapy may offer to children affected by neuroblastoma."

Neuroblastoma Alliance UK's Chief Executive, Alison Moy, agreed, "We are really excited to be involved in this collaboration, which is taking parent advocacy and the involvement of charities in furthering research to a new level. As neuroblastoma only affects children, it is not considered a common cancer and therefore research funding has been limited. We believe that children should be able to access the best possible treatment, wherever that may be and that's why we support families to access clinical treatment abroad. We hope that through the INBRC project, more children from the U.K. will be able get effective treatment, wherever that trial is taking place."

###

Solving Kids' Cancer

Created by two fathers who lost children to pediatric cancer, Solving Kids' Cancer is committed to significantly improving survivorship of the deadliest childhood cancers. 100% of all donations are used to find, fund, and manage clinical trials and scientific programs to rapidly develop more effective and less toxic treatments. Solving Kids' Cancer is a 501(c)(3) public charity. To learn more about our work, please visit www.solvingkidscancer.org.

J-A-C-K

Joining Against Cancer in Kids (J-A-C-K) provides advice and support for children and families wishing to undertake innovative or experimental clinical trials, treatments for neuroblastoma. For more information, visit www.J-A-C-K.org.

Neuroblastoma Alliance UK

Established in 2006, the Neuroblastoma Alliance UK helps children and families affected by neuroblastoma by providing financial assistance for children's treatment and support to families affected by the disease, as well as funding research. The charity, which was until recently known as the 2Simple Trust, has helped fund treatment for 21 children abroad. This is more than any other neuroblastoma charity in the UK. See more at www.childrenscancer.org.uk

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-03/skc-pcc030413.php

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